ANIMATION

Vasopressin V2-Receptor Blockage

Share this animation:

Hyponatremia is a condition characterized by low sodium concentration in blood serum. This may be caused by overactivity of anti-diuretic hormone, which results in increased reabsorption of water from the collecting duct. Tolvaptan is an FDA-approved antagonist of the vasopressin V2-receptor. Inhibition of this receptor prevents the expression of aquaporin channels along the collecting duct, promoting diuresis and correcting sodium levels in serum.

Share It:
Contact XVIVO

Client


Otsuka

I wanted to share with you the news I just heard that the fabulous image you prepared for us has been selected for the cover of Cell! This is wonderful testimony to your talent and ability to rapidly reduce an idea to a stunning illustration. We were particularly impressed with your responsiveness and ability to quickly make significant modifications to meet our external deadlines. Many thanks for all your help, and congratulations!

Richard P. Lifton: Chairman, Yale University Department of Genetics; Sterling Professor of Genetics, Medicine and Molecular Biophysics and Biochemistry; Investigator, Howard Hughes Medical Institute
Share this animation: