Work / Animation / Tumor Treating Fields
XVIVO and Novocure have teamed up to illustrate their breakthrough technology for the non-invasive treatment of solid tumors. Tumor Treating Fields, or TTFields, are alternating electric fields that disrupt and trigger death of cancerous cells.
TTFields are non-invasive and function through non-chemical means. The electric fields are produced using two pairs of transducer arrays, and rely solely on physical forces to disrupt cell division. High frequency alternating electric currents cause polarizable macromolecules to align with the field, arresting molecules and mechanisms necessary for cell division. Concurrently, high electric field densities caused by the shape of dividing cells cause organelles to migrate to the mitotic furrow, causing structural disruption. By alternating the direction of the currents between two pairs of arrays, a maximal range of cell orientations can be targeted for disruption.
The specificity and low-toxicity of TTFields makes it an attractive option for treating solid tumors. It is currently approved for use in the U.S. and Europe for the treatment of glioblastoma multiforme, an extremely aggressive brain cancer, alongside conventional therapy.
John Lapolla, Asante Communications, LLC
XVIVO is in a unique class of crackerjack design companies with honest, capable, supremely talented artists, graphic designers, strategists, and project managers, all of whom are committed to excellence in animation. They understand the unique power of this still evolving art form, its ability to distill otherwise unapproachable biochemical data, and to make it available to the untrained marketing professional, all the while preserving the integrity of the science for the experts who have committed their life’s work to drug discovery and development. Ain’t it easy when you know how to do it?