ANIMATION

JAK Pathway Signaling

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For Incyte, XVIVO developed a chaptered animation program on the JAK signaling pathway. Janus kinases (JAK) are enzymes that mediate signaling of several important drivers of myeloproliferative neoplasms (MPNs), other hematological malignancies, and inflammatory diseases. This animation focuses on four JAK enzymes: JAK1, 2, 3 and TYK2. Aberrant activation of the JAK-STAT pathway has been documented in a variety of cancers. This clip illustrates normal JAK pathway activation and the associated downstream signaling.

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Incyte

I came to XVIVO with only a few basic thoughts, and from these ideas, they worked out an excellent and striking image that perfectly conveyed the scientific point. I was very pleased with the experience, and I would recommend XVIVO to anyone that wants to explain complicated scientific ideas with clear and professional images.

Jeff Moffitt, Graduate Student, Bustamante Lab, Department of Physics, University of California-Berkeley
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