ANIMATION

JAK Pathway Signaling

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For Incyte, XVIVO developed a chaptered animation program on the JAK signaling pathway. Janus kinases (JAK) are enzymes that mediate signaling of several important drivers of myeloproliferative neoplasms (MPNs), other hematological malignancies, and inflammatory diseases. This animation focuses on four JAK enzymes: JAK1, 2, 3 and TYK2. Aberrant activation of the JAK-STAT pathway has been documented in a variety of cancers. This clip illustrates normal JAK pathway activation and the associated downstream signaling.

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Incyte

My experience working with XVIVO can be summed up in one word: Confidence. Confidence in the depth of scientific knowledge they contributed, this knowledge only enhanced the end product, was evident as a core competency from our initial discussions even before engaging them for the production, and inspired our team because they were collaborating with a partner who is as dedicated to the science of the story as they are.

VP, Director of Production, JUICE Pharma Advertising
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