ANIMATION

Glutamate Modulation

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Glutamate is the most abundant excitatory neurotransmitter in the brain. Release of glutamate is essential for normal function of neurons, but the levels of this neurotransmitter must be tightly regulated to avoid toxic effects on neurons.

XVIVO partnered with Biohaven to animate the glutamate story. The script details normal glutamate signaling, dysfunctional glutamate signaling and the mechanism of action of Biohaven’s investigational agent trigriluzole, a novel neuroprotective agent to modulate glutamate neurotransmission. Trigriluzole is expected to reduce the neurotoxicity associated with excessive glutamatergic excitation, which is implicated in many disorders involving the central nervous system.

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Glutamate Modulation

Through their creative prowess and technical mastery, XVIVO is defining and redefining the very frontier of scientific animation. As science and medicine explore increasingly remote realms, their work provides a vital link allowing researchers and the general public to grasp visually an astonishing landscape of new possibilities.

Brian Greene, Professor Mathematics & Physics, Columbia University
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