ANIMATION

Apoptosis and BCL-2

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ABT-199/GDC-0199 is a small molecule drug in co-development by Abbvie and Genentech for the selective inhibition of BCL-2, a key regulator of cellular apoptosis. BCL-2, part of the larger BCL-2 family, is responsible for the sequestration of pro-apoptopic proteins along the mitochondrial membrane. Displacement of these proteins from BCL-2 in cancerous cells may prime these cells for apoptosis.

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Abbvie; Genentech

I LOVED XVIVO’s reel. I thought their attention to detail was amazing – the way they took the time to add subtle movements to cell walls or the primary visual was exactly what i was looking for but assumed they were too expensive – to my delight they were well within budget + they were also the clients first choice.

Art Director, DH Art Direction & Design, XCOVERY
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