ANIMATION

Apoptosis and BCL-2

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ABT-199/GDC-0199 is a small molecule drug in co-development by Abbvie and Genentech for the selective inhibition of BCL-2, a key regulator of cellular apoptosis. BCL-2, part of the larger BCL-2 family, is responsible for the sequestration of pro-apoptopic proteins along the mitochondrial membrane. Displacement of these proteins from BCL-2 in cancerous cells may prime these cells for apoptosis.

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Abbvie; Genentech

I just want to thank you again for the wonderful job you did for Zirus in designing our award winning animation on viral replication. If it was just how the animation looked and was received by others, you would be great. But what mattered more was how you became trusted partners with us in helping us create value and spreading our message. You have been invaluable to Zirus and we very much appreciate your contributions, talents and professionalism.

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