XVIVO worked closely with Incyte to develop a chaptered animation program on JAK pathway signaling. Janus kinases (JAK) are enzymes that mediate signaling of several important drivers of myeloproliferative neoplasms (MPNs), other hematological malignancies and inflammatory diseases. There are four JAK enzymes: JAK1, 2, 3 and TYK2.  Aberrant activation of the JAK-STAT pathway has been documented in a variety of cancers. This clip features a selection from the full animation showing normal JAK pathway activation and downstream signaling.

“I just want to thank you again for the wonderful job you did for Zirus in designing our award winning animation on viral replication. If it was just how the animation looked and was received by others, you would be great. But what mattered more was how you became trusted partners with us in helping us create value and spreading our message. You have been invaluable to Zirus and we very much appreciate your contributions, talents and professionalism.”
David G. Perryman, President and CEO, Zirus, Inc.