Work / Animation / Vasopressin V2-Receptor Blockage
Hyponatremia is a condition characterized by low sodium concentration in blood serum. This may be caused by overactivity of anti-diuretic hormone, which results in increased reabsorption of water from the collecting duct. Tolvaptan is an FDA-approved antagonist of the vasopressin V2-receptor. Inhibition of this receptor prevents the expression of aquaporin channels along the collecting duct, promoting diuresis and correcting sodium levels in serum.
Les Szabo, Pure Potential Media
XVIVO’s animations are the ideal integration of art and science. The work they did for us was truly groundbreaking.