ANIMATION

JAK Pathway Signaling

For Incyte, XVIVO developed a chaptered animation program on the JAK signaling pathway. Janus kinases (JAK) are enzymes that mediate signaling of several important drivers of myeloproliferative neoplasms (MPNs), other hematological malignancies, and inflammatory diseases. This animation focuses on four JAK enzymes: JAK1, 2, 3 and TYK2. Aberrant activation of the JAK-STAT pathway has been documented in a variety of cancers. This clip illustrates normal JAK pathway activation and the associated downstream signaling.

Client


Incyte

We were very pleased with the final product, the speed at which you team completed the rounds from story board to rough animation/final animation, and the flexibility to change parts of the animation when our client came in with additional changes at the last hour. Our client was also very happy with the final product. In addition, Mike and Roz were very buttoned up with the communication flow, and always available when we needed to discuss changes. It would be my pleasure to provide a recommendation if needed.

Dr. Chris. Tobias, OmniGuide Project, Dudnyk