ANIMATION

JAK Pathway Signaling

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For Incyte, XVIVO developed a chaptered animation program on the JAK signaling pathway. Janus kinases (JAK) are enzymes that mediate signaling of several important drivers of myeloproliferative neoplasms (MPNs), other hematological malignancies, and inflammatory diseases. This animation focuses on four JAK enzymes: JAK1, 2, 3 and TYK2. Aberrant activation of the JAK-STAT pathway has been documented in a variety of cancers. This clip illustrates normal JAK pathway activation and the associated downstream signaling.

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Client


Incyte

Working with XVIVO was an excellent choice, we are so happy with the finished animation. It was particularly satisfying showing it to the executive team and hearing, ‘it looks marvelous’.

Senior Researcher, FrieslandCampina
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