For Incyte, XVIVO developed a chaptered animation program on the JAK signaling pathway. Janus kinases (JAK) are enzymes that mediate signaling of several important drivers of myeloproliferative neoplasms (MPNs), other hematological malignancies, and inflammatory diseases. This animation focuses on four JAK enzymes: JAK1, 2, 3 and TYK2. Aberrant activation of the JAK-STAT pathway has been documented in a variety of cancers. This clip illustrates normal JAK pathway activation and the associated downstream signaling.
Ozgur Sahin, PI, Nanomechanical Sensing, Rowland Institute at Harvard University
XVIVO has done an outstanding job for us. They engaged in our graphical design project with enthusiasm and took it to a level well beyond our imagination!