JAK Pathway Signaling

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For Incyte, XVIVO developed a chaptered animation program on the JAK signaling pathway. Janus kinases (JAK) are enzymes that mediate signaling of several important drivers of myeloproliferative neoplasms (MPNs), other hematological malignancies, and inflammatory diseases. This animation focuses on four JAK enzymes: JAK1, 2, 3 and TYK2. Aberrant activation of the JAK-STAT pathway has been documented in a variety of cancers. This clip illustrates normal JAK pathway activation and the associated downstream signaling.



We have only positive feedback for you and your team. This experience has been great and trouble-free from the beginning. I would not hesitate to refer another company to XVIVO should they need help with scientific and medical illustration. Thanks for the great work.

Operations Manager, C3 Jian