Work / Animation / Fibroblasts
Oxidative stress in the inflamed wound environment causes premature fibroblast aging, which can lead to the breakdown and insufficient production of the extracellular matrix. The presence of non-senescent fibroblasts can help defend against pathogens in the wound while helping to promote matrix regeneration through the release of signaling factors.These fibroblasts produce molecules including Type I and Type III collagen, fibronectin, and tenascin, which in combination provide structural tissue support while protecting the wound and directly influencing the behavior of nearby cells to promote regeneration.
David G. Perryman, President and CEO, Zirus, Inc.
I just want to thank you again for the wonderful job you did for Zirus in designing our award winning animation on viral replication. If it was just how the animation looked and was received by others, you would be great. But what mattered more was how you became trusted partners with us in helping us create value and spreading our message. You have been invaluable to Zirus and we very much appreciate your contributions, talents and professionalism.