Work / Animation / EGFRvIII(+) Glioblastoma
Glioblastoma multiforme is considered one of the most aggressive cancers, with an estimated 5-year survival rate of less than 5%. It has been found that approximately 30% of glioblastoma tumors selectively express the EGFRvIII variant receptor, the activity of which contributes to tumor growth, resistance to apoptosis, and tumor angiogenesis. The persistence of EGFRvIII on glioblastoma cells suggest it may be a viable candidate for more targeted therapeutic approaches.
Alain Viel PhD, Senior Lecturer and Director of Undergraduate Research in Molecular and Cellular Biology, Harvard University
I was impressed by the ability of the XVIVO team to transform all the structural information and the very detailed sequence of molecular events that I assembled in a story-board into a visually pleasing work of art.