ANIMATION

EGFRvIII(+) Glioblastoma

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Glioblastoma multiforme is considered one of the most aggressive cancers, with an estimated 5-year survival rate of less than 5%. It has been found that approximately 30% of glioblastoma tumors selectively express the EGFRvIII variant receptor, the activity of which contributes to tumor growth, resistance to apoptosis, and tumor angiogenesis. The persistence of EGFRvIII on glioblastoma cells suggest it may be a viable candidate for more targeted therapeutic approaches.

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Through their creative prowess and technical mastery, XVIVO is defining and redefining the very frontier of scientific animation. As science and medicine explore increasingly remote realms, their work provides a vital link allowing researchers and the general public to grasp visually an astonishing landscape of new possibilities.

Brian Greene, Professor Mathematics & Physics, Columbia University
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