Bavituximab Mechanism of Action (MOA)

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Together with Peregrine, we helped depict the mechanism of action behind Bavituximab, an investigational treatment that helps the body recognize cancer cells. Upregulated expression of phosphatidylserine by cancer cells contributes to their ability to avoid destruction by the immune system. Bavituximab targets phosphatidylserine, thereby encouraging active immune activity in cancerous environments.

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Peregrine Pharmaceuticals, Inc.

I wanted to share with you the news I just heard that the fabulous image you prepared for us has been selected for the cover of Cell! This is wonderful testimony to your talent and ability to rapidly reduce an idea to a stunning illustration. We were particularly impressed with your responsiveness and ability to quickly make significant modifications to meet our external deadlines. Many thanks for all your help, and congratulations!

Richard P. Lifton: Chairman, Yale University Department of Genetics; Sterling Professor of Genetics, Medicine and Molecular Biophysics and Biochemistry; Investigator, Howard Hughes Medical Institute
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